Product Parameters
Item |
Information |
Chemical Name |
Nobiletin |
Synonyms |
Hexamethoxyflavone, 3',4',5,6,7,8-Hexamethoxyflavone, 5,6,7,8,3',4'-Hexamethoxyflavone, etc. |
CAS Number |
478-01-3 |
Molecular Formula |
C21H22O8 |
Molecular Weight |
402.40 |
Appearance |
White to slightly yellow crystalline powder |
Melting Point |
Not specified |
Solubility |
Soluble in methanol, slightly soluble in water (13.39 mg/L @ 25 °C) |
Customs Tariff Classification (HS Code) |
2932.99.7000 |
Applications |
A citrus flavonoid with anti-inflammatory and anti-tumor activities, used in research and as a reference standard |
Pharmaceutical and Medical Applications
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Neuroprotection: Nobiletin has been shown to improve cognitive deficits and pathological features of Alzheimer's disease (AD), such as amyloid-beta (Aβ) pathology, hyperphosphorylation of tau, and oxidative stress. It also enhances memory and protects against neurodegeneration in animal models of AD and Parkinson's disease (PD).
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Anti-inflammatory and Antioxidant Effects: Nobiletin exhibits strong anti-inflammatory and antioxidant properties, which can help mitigate the effects of various inflammatory and oxidative stress-related conditions.
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Cardiovascular Protection: It has been reported to lower cholesterol and reduce the risk of atherosclerosis, thus offering cardiovascular benefits.
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Anti-tumor and Cancer Chemoprevention: Nobiletin has demonstrated anti-tumor and cancer chemopreventive activities, making it a potential candidate for cancer treatment and prevention.
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Metabolic Syndrome: Nobiletin can prevent metabolic syndrome by enhancing circadian rhythms and activating specific genes and proteins involved in metabolism.
Research and Experimental Use
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Matrix Metalloproteinase Inhibitor: Nobiletin acts as a matrix metalloproteinase inhibitor, which is useful in research related to tissue remodeling and degradation.
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Reference Standard: It is used as a reference standard in analytical chemistry and biological research to study the effects of similar compounds.
Other Applications
Safety and Handling
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Nobiletin is generally considered safe for experimental and research use. However, it should be handled with care, especially in laboratory settings, to avoid potential health risks associated with its strong biological activities.
Describe
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Chongqing Yuhan Technology Co., Ltd. -- Bridging High-Quality Chemicals to Global Markets
About Us
Since 2017, Chongqing Yuhan Technology has grown from a local supplier to a leading international trader of chemical raw materials and reagents. We serve diverse industries including electric power, metallurgy, agriculture, pharmaceuticals, textiles, plastics, and research institutions, with a global client base.
Our Business Scope
We offer a wide range of chemical products, specializing in high-purity acids, perovskite materials, and hazardous chemicals. Our focus on bulk and high-performance materials ensures we meet the unique needs of our clients with customized solutions.
Our Strengths
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Diverse Product Lines: Comprehensive range of chemicals for one-stop procurement.
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Market Competitiveness: Strong market position with long-term partnerships.
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Looking Forward
We are committed to continuous improvement, offering more professional and efficient solutions. We aim to expand our international presence and become the preferred partner for high-quality chemical raw materials and reagents globally.
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Industry Reputation: Recognized for professionalism and reliability.
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Risk Control: Effective management of safety and environmental risks.
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Partner Trust: Trusted for securing favorable terms and prices.








Q1: Can I get some samples?
A: Yes, sure. Usually, we can provide free samples for less than 5 kg, but the customer needs to pay for the shipping.
Q2: What is your MOQ?
A: The minimum order quantity varies for different products, with most requiring a minimum of 1 ton. However, we can accommodate smaller quantities, such as 100kg, with a 100% sample charge.
Q3: How to confirm product quality before placing an order?
A: You can obtain free samples of the products, but you need to cover the shipping fee or arrange for the samples to be sent to us by express. Additionally, you can provide us with your product specifications and requirements, and we will manufacture the products accordingly.
Q4: Is there a discount for bulk purchases? How much is the discount?
A: Yes, we offer discounts for bulk purchases. The discount is determined by evaluating factors such as purchase volume, product type, and cooperation period. Generally, the larger the purchase volume, the greater the discount.
Q5: How do I start paying?
A: Payment can be made by wire transfer, Western Union, PayPal, Visa, Mastercard, T/T, Apple Pay, Google Pay, etc.
Q6: What is the shipping time?
A: We ship the products out within 1-3 days and provide a tracking number. Shipping time varies by country.
Q7: What qualifications and certifications does the company have? Such as ISO certification, etc.
A: Our supply manufacturers hold several authoritative certifications to ensure our products and services meet international standards and industry regulations. This includes the ISO 9001 Quality Management System certification, which indicates we have reached internationally recognized levels in product quality control, production process management, and continuous improvement, providing stable and reliable quality assurance for customers.
Q8: How about the after-sale service of products?
A: After purchasing products from our company, you will be supported by our professional technical team and after-sales team, who will help solve any problems you may encounter.