Product Parameters
| CAS Number |
1821-12-1 |
| Chemical Name |
4-Phenylbutyric Acid |
| Synonyms |
4-Phenylbutanoic acid, Benzenebutyric acid |
| Molecular Formula |
C10H12O2 |
| Molecular Weight |
164.2 |
| Appearance |
White to almost white powder to crystal |
| Melting Point |
49.0 to 53.0 °C |
| Boiling Point |
175 °C/20 mmHg |
| Solubility |
Insoluble in water; 33 mg/mL in DMSO |
| Storage Conditions |
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Purity |
>98.0% (GC) |
| Application |
Inhibitor of HDAC, used in cancer and infection research |
1. Medical Applications
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Treatment of Urea Cycle Disorders: 4-Phenylbutyric acid is used as a nitrogen-scavenging agent in the treatment of urea cycle disorders. It helps to lower blood ammonia levels by providing an alternative pathway for nitrogen excretion.
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Cancer Therapy: It acts as a histone deacetylase (HDAC) inhibitor. By inhibiting HDAC, it can induce cell cycle arrest, apoptosis, and differentiation in cancer cells, making it a potential therapeutic agent for various types of cancers.
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Neurodegenerative Diseases: Research is being conducted on its potential use in treating neurodegenerative diseases such as Huntington's disease. It may help to reduce the accumulation of toxic proteins and protect neurons.
2. Research Applications
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Biochemical Research: It is used as a tool in biochemical studies to investigate the role of HDAC in various cellular processes. Researchers can use it to study gene expression, cell signaling pathways, and the regulation of cell cycle and apoptosis.
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Drug Development: It serves as a starting material or intermediate in the development of new drugs. Its HDAC inhibitory activity can be exploited to design more potent and selective inhibitors for specific therapeutic targets.
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Cell Culture: In cell culture experiments, it can be added to the culture medium to study its effects on cell growth, differentiation, and survival. It can also be used to induce specific cellular responses for mechanistic studies.
3. Industrial Applications
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Pharmaceutical Manufacturing: It is used in the industrial production of pharmaceuticals. It may be a key raw material or intermediate in the synthesis of certain drugs, especially those targeting HDAC or related pathways.
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Chemical Synthesis: It can be used as a building block in the synthesis of other organic compounds. Its carboxylic acid group and phenyl ring provide opportunities for various chemical reactions to produce derivatives with different functional groups and properties.
4. Other Potential Uses
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Metabolic Studies: It can be used in metabolic studies to investigate the effects of nitrogen metabolism and ammonia detoxification in different biological systems.
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Toxicology Research: It can be used to study the toxic effects of ammonia and other nitrogenous compounds in the body, as well as the protective effects of nitrogen-scavenging agents like 4-phenylbutyric acid.
Describe
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Chongqing Yuhan Technology Co., Ltd. -- Bridging High-Quality Chemicals to Global Markets
About Us
Since 2017, Chongqing Yuhan Technology has grown from a local supplier to a leading international trader of chemical raw materials and reagents. We serve diverse industries including electric power, metallurgy, agriculture, pharmaceuticals, textiles, plastics, and research institutions, with a global client base.
Our Business Scope
We offer a wide range of chemical products, specializing in high-purity acids, perovskite materials, and hazardous chemicals. Our focus on bulk and high-performance materials ensures we meet the unique needs of our clients with customized solutions.
Our Strengths
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Diverse Product Lines: Comprehensive range of chemicals for one-stop procurement.
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Market Competitiveness: Strong market position with long-term partnerships.
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Looking Forward
We are committed to continuous improvement, offering more professional and efficient solutions. We aim to expand our international presence and become the preferred partner for high-quality chemical raw materials and reagents globally.
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Industry Reputation: Recognized for professionalism and reliability.
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Risk Control: Effective management of safety and environmental risks.
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Partner Trust: Trusted for securing favorable terms and prices.
Q1: Can I get some samples?
A: Yes, sure. Usually, we can provide free samples for less than 5 kg, but the customer needs to pay for the shipping.
Q2: What is your MOQ?
A: The minimum order quantity varies for different products, with most requiring a minimum of 1 ton. However, we can accommodate smaller quantities, such as 100kg, with a 100% sample charge.
Q3: How to confirm product quality before placing an order?
A: You can obtain free samples of the products, but you need to cover the shipping fee or arrange for the samples to be sent to us by express. Additionally, you can provide us with your product specifications and requirements, and we will manufacture the products accordingly.
Q4: Is there a discount for bulk purchases? How much is the discount?
A: Yes, we offer discounts for bulk purchases. The discount is determined by evaluating factors such as purchase volume, product type, and cooperation period. Generally, the larger the purchase volume, the greater the discount.
Q5: How do I start paying?
A: Payment can be made by wire transfer, Western Union, PayPal, Visa, Mastercard, T/T, Apple Pay, Google Pay, etc.
Q6: What is the shipping time?
A: We ship the products out within 1-3 days and provide a tracking number. Shipping time varies by country.
Q7: What qualifications and certifications does the company have? Such as ISO certification, etc.
A: Our supply manufacturers hold several authoritative certifications to ensure our products and services meet international standards and industry regulations. This includes the ISO 9001 Quality Management System certification, which indicates we have reached internationally recognized levels in product quality control, production process management, and continuous improvement, providing stable and reliable quality assurance for customers.
Q8: How about the after-sale service of products?
A: After purchasing products from our company, you will be supported by our professional technical team and after-sales team, who will help solve any problems you may encounter.
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