Androgen Receptor Antagonists Latex Gel Pharmaceuticals Hair Growth Hair Loss Acne Treatment Clascoterone CAS 19608-29-8

• Customization: Available
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Model NO.: yh-klst
• Grade Standard: Industrial Grade
• Purity: 98/99%
• Freight1: Small Quantity Logistics or Air Transport
• Freight2: Ocean Freight
• Freight3: Pick up
• Free Sample: Available
• Environmental Protection: Yes
• Belong: Yuhan Chem
• Lead Time: Within 7 Days
• Storagemethod: Sealed Container
• Packaging: Sealed Packaging
• Odor: Odorless
• Storage2: Cool Dry Place
• Stability: Excellent
• Port1: Chongqing
• MOQ: 1kg
• Transport Package: 1kg Minimum Order Quantity
• Specification: Sealing, on request
• Trademark: Customizable
• Origin: China
• HS Code: 2939909090
• Production Capacity: 10000ton/Year

Product Description

Product Parameters

  

Property	Value
CAS Number	19608-29-8
Molecular Formula	C24H34O5
Molecular Weight	402.52
English Name	Clascoterone
English Synonyms	Cortexolone 17α-propionate, CB-03-01, Winlevi, 17α-propionate
Appearance	White to light yellow solid
Melting Point	Not specified
Boiling Point	Not specified
Density	Not specified
Solubility	Soluble in DMSO (≥ 100 mg/mL)
Storage Conditions	Powder: -20°C (3 years), 4°C (2 years); In solvent: -80°C (2 years), -20°C (1 year)
Application	Topical androgen receptor antagonist; used for treating acne and androgenetic alopecia
Customs Code	2939909090

Product Description

 

Clascoterone is a novel topical androgen receptor antagonist with several important applications, particularly in dermatology. Here are its key uses and functions:

• Topical Androgen Receptor Antagonist:
  • Mechanism of Action: Clascoterone acts as a selective androgen receptor antagonist. It binds to the androgen receptor and blocks the effects of androgens such as testosterone and dihydrotestosterone (DHT) on the skin. This mechanism helps reduce the production of sebum and other androgen-dependent processes that contribute to acne and hair loss.
• Treatment of Acne:
  • Acne Vulgaris: Clascoterone is used to treat acne vulgaris, a common skin condition characterized by the formation of pimples, blackheads, and whiteheads. By inhibiting the androgen receptors in the sebaceous glands, Clascoterone reduces sebum production, which is a primary cause of acne.
  • Clinical Trials: Studies have shown that Clascoterone is effective in reducing the number of inflammatory and non-inflammatory acne lesions. It has been demonstrated to be safe and well-tolerated in clinical trials.
• Treatment of Androgenetic Alopecia:
  • Hair Loss: Clascoterone is also being investigated for the treatment of androgenetic alopecia, commonly known as male pattern baldness. It works by blocking the effects of DHT on hair follicles, which helps prevent hair loss and promote hair growth.
  • Clinical Trials: Ongoing clinical trials are evaluating the efficacy and safety of Clascoterone for treating androgenetic alopecia. Preliminary results indicate that it may be a promising treatment option for this condition.
• Topical Application:
  • Formulation: Clascoterone is formulated as a topical cream or gel, which allows for targeted delivery to the affected areas of the skin. This formulation minimizes systemic absorption and potential side effects.
  • Ease of Use: The topical application makes it convenient for patients to use, requiring application once or twice daily to the affected areas.

Safety and Side Effects

• Safety Profile: Clascoterone has been shown to be safe and well-tolerated in clinical trials. It has a favorable safety profile compared to other treatments for acne and hair loss.
• Side Effects: Common side effects are generally mild and may include skin irritation, dryness, or itching at the application site. These side effects are typically transient and resolve on their own.

Clinical Trials and Regulatory Status

• Clinical Trials: Clascoterone has undergone extensive clinical trials to evaluate its efficacy and safety in treating acne and androgenetic alopecia. These trials have demonstrated its effectiveness in reducing acne lesions and promoting hair growth.
• Regulatory Approval: Clascoterone has received regulatory approval in several countries for the treatment of acne. It is also under review for the treatment of androgenetic alopecia.

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FAQ

Q1: Can I get some samples?
A: Yes, sure. Usually, we can provide free samples for less than 5 kg, but the customer needs to pay for the shipping.

Q2: What is your MOQ?
A: The minimum order quantity varies for different products, with most requiring a minimum of 1 ton. However, we can accommodate smaller quantities, such as 100kg, with a 100% sample charge.

Q3: How to confirm product quality before placing an order?
A: You can obtain free samples of the products, but you need to cover the shipping fee or arrange for the samples to be sent to us by express. Additionally, you can provide us with your product specifications and requirements, and we will manufacture the products accordingly.

Q4: Is there a discount for bulk purchases? How much is the discount?
A: Yes, we offer discounts for bulk purchases. The discount is determined by evaluating factors such as purchase volume, product type, and cooperation period. Generally, the larger the purchase volume, the greater the discount.

Q5: How do I start paying?
A: Payment can be made by wire transfer, Western Union, PayPal, Visa, Mastercard, T/T, Apple Pay, Google Pay, etc.

Q6: What is the shipping time?
A: We ship the products out within 1-3 days and provide a tracking number. Shipping time varies by country.

Q7: What qualifications and certifications does the company have? Such as ISO certification, etc.
 A: Our supply manufacturers hold several authoritative certifications to ensure our products and services meet international standards and industry regulations. This includes the ISO 9001 Quality Management System certification, which indicates we have reached internationally recognized levels in product quality control, production process management, and continuous improvement, providing stable and reliable quality assurance for customers.

Q8: How about the after-sale service of products?
A: After purchasing products from our company, you will be supported by our professional technical team and after-sales team, who will help solve any problems you may encounter.